Le Clos was admitted to hospital in Durban on Monday to have four wisdom teeth removed, just two weeks before the biennial spectacle.
While he was not undergoing a major operation, his management team remained cautious about his recovery.
“We haven’t even booked yet for Doha because we’re not sure what to expect,” said his father, Bert le Clos.
“Surgery is surgery, so we don’t want to confirm until we’re sure, but we should know by tomorrow whether he’ll recover in time.”
Le Clos said previously he would target three gold medals in Doha, in the 50m, 100m and 200m butterfly events.
The 22-year-old South African displayed fine form in the international short course campaign this season, winning the overall Fina World Cup series title for the third time in his career.