It was the worst possible start to the Cheetahs tour who have now suffered their third straight defeat.
They also lost captain Francois Uys just prior to the game with a back strain, with the leadership taken over by flanker Heinrich Brussow.
They also lost Springbok flank Oupa Mohoje late in the game when he was carried off on a medical stretcher.
The Crusaders in contrast have recorded their second straight big win over an SA side after beating the Lions 34-6 last weekend and now they head to Loftus next weekend to take on the Bulls.
After putting up a good show in the first half when they lead 14-10 at halftime against all odds, the Cheetahs were made to pay for harsh yellow cards to fullback Willie le Roux and prop Coenie Oosthuizen.
Le Roux was send off for an attempted high tackle while Oosthuizen was according to referee Andrew Lees guilty of repeated scrum infringements against strongman Wyatt Crockett.
A blitzkrieg of 21 points inside 10 minutes early in the second half sealed matters for the Crusaders with a penalty try, and more tries by fullback Israel Dagg and centre Dan Carter created a decisive 31-14 advantage.
Four more tries followed by wing Nemani Nadolo, replacement David Havilli and a second each by flank Jordan Taufua and Carter completed the rout.
In the first half the Cheetahs looked very promising after Taufua scored the first try in the 19th minute for a 7-0 Crusaders lead.
First centre Francois Venter scored an intercept try in the 29th minute and barely four minutes later his midfield partner Johann Sadie scored a gem after brilliant attacking work from wing Raymond Rhule to go into a surprising 14-7 lead.
Carter narrowed the gap with a penalty just before the halftime hooter went, but the Crusaders left their demolition job for the second 40 …