Bok team doctor Craig Roberts said this afternoon Le Roux has suffered a suspected fractured cheekbone, while Du Plessis over extended his knee and hamstring muscle against England at the weekend.
They were due to be sent for further examinations following the Boks training session in the Italian city later today.
The rest of the squad are only suffering from the usual bumps and bruises.
“It’s always easier after a win, but there are guys we’ll manage who have been carrying a heavy workload, like Beast Mtawarira who got quite serious cramps towards the end of the game,” said Roberts.
Bok backline coach Ricardo Loubscher said the performance of Pat Lambie at flyhalf last weekend came as no surprise to the Bok brains trust.
“The discussion in the past has been that Pat is a world-class player, he can slot in anywhere. In training he has been good and he did really well last weekend too, so we are really happy with him,” said Loubscher.
“This week is about further improvement and if you look at the game last weekend, we are happy with the win, but there are still areas where we can get better, like in terms of finishing where we had a few opportunities.”
The second Bok try by scrumhalf Cobus Reinach was also a result of hard work at training, he said.
“It was pure brilliance from Pat, we spoke the whole of last week about identifying space on the field, and Cobus’ support on the inside, the right time, right place,“ he said.
“It was pure instinct from Willie, he will look to attack the space and sniff out opportunities, and it was one of those instances where we had an opportunity which we used and I think we used it well.”