Nelson Mandela Children’s Fund warns of crisis as US funding cuts to PEPFAR threatens lives
The recent reductions in PEPFAR funding from the US government has put South Africa’s vital HIV and healthcare services at risk, leaving thousands exposed and organisations seeking solutions

A shadow of uncertainty hangs over South Africa’s most vulnerable as the abrupt changes to the US President’s Emergency Plan for AIDS Relief (PEPFAR) funding threatens to upend crucial healthcare services. The Nelson Mandela Children’s Fund (NMCF) has expressed deep concern, warning that the limited waiver granted by the US administration is nowhere near enough to safeguard those who rely on this support.
For years, PEPFAR has been a lifeline, providing essential funding to organisations fighting HIV/AIDS, tuberculosis, and other life-threatening diseases. But now, restrictions on funding have left many in the sector questioning their survival. While critical services like HIV treatment and mother-to-child transmission prevention remain covered, a long list of exclusions, ranging from family planning to administrative costs, has sparked fear of widespread closures and job losses.
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“This development is unfortunate, and arises at a time when such funding is essential across our communities,” said Karl Muller, chief programmes officer at NMCF. “Thousands of South Africans have benefited from this funding over the years, yet we behave as though it’s business as usual.”
Ripple effects on healthcare and employment
The consequences of these cuts stretch far beyond the walls of affected organisations. The country’s unemployment crisis, already at alarming levels, will deepen as workers from these institutions find themselves without jobs. Families, children, and those in desperate need of ongoing medical support will feel the ripple effect.

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Funding reductions are not a new challenge. International aid has been shrinking for years due to economic constraints and shifting priorities. However, the abrupt nature of PEPFAR’s limitations leaves organisations scrambling for solutions. Without financial backing for administration, outreach efforts, and key medical services, their ability to function is severely compromised.
Many in the sector share Muller’s concerns. “All funding needs to be properly accounted for,” he acknowledged. “But what we are witnessing now is an increasingly stringent approach that may do more harm than good.”
A call for urgent review
While the official reasoning behind the restrictions has not been fully detailed, the message is clear: PEPFAR will no longer operate as the reliable support system it once was. For the thousands who depend on it, this decision is more than a bureaucratic adjustment; it is a potential death sentence.
As South African organisations brace for the fallout, the hope remains that international stakeholders will reconsider the long-term impact of these funding constraints. For now, uncertainty reigns, and the lives of many are uncertain.
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