Six people have been killed this morning  in what the KZN Emergency Medical services paramedics describe as a major accident on the N11, between Newcastle and Ladysmith.

The exact location of the crash, is at the Driefontien turn off, about two kilometres from Ladysmith.

Two men and four women died and KZN EMS paramedics together with the paramedics from a private ambulance service have treated three people who have survived the initial impact of the collision. One of these patients is a woman, who is critically injured. While two men, who were occupants of the truck, sustained serious and minor injuries, respectively.

The paramedics worked together to treat the injured patients at the scene before the patients were transported to hospital for continued medical care.

The cause of the crash, which left the road closed, is being investigated by the police.