Siphesihle Ndlovu of Maritzburg United (Aubrey Kgakatsi/BackpagePix)
A place in the last eigh of the competition and bragging rights will be at up for grabs when the KwaZulu-Natal sides meet.
Eagles beat Happy Wanderers in the last round 1-0 and will be hoping to stun the high-flying Team of Choice in front of their home crowds.
Maritzburg overcame a stubborn Swallows FC and they will now be vigilant against another side from the lower division.