The cause of the accident was not yet clear, however, three vehicles collided, leaving one ripped to shreds.
Two people were transported to hospital in a critical condition while another four suffered other injuries, Best Care Ambulance spokesperson Xander Loubser said.
“Traffic is at a standstill in both directions of the highway as multiple paramedics worked through the complex scene,” he said.
According to documents found in the wrecked Mercedes, the vehicle was bought from an auction but was still due for repairs.
Police would be investigating the details that led to the accident.